SIMPREDICT (WORKING PAPER) Pleiotropy graph calculate

Translating C-statistics into risk-based performance


Y axis: Choose effect size or a threshold
Click and see results by incidence per 100,000 person-years
Effect size Observed HR per SD
Threshold based on risk >1% >5% >10% over 10 years
Threshold based on rank >90th >75th >50th percentile